Clodronate SUV PEG Liposomes
Artificial spheres consisting of a single phospholipid bilayer encapsulating an aqueous PBS (phosphate buffered saline) solution containing clodronate. A special PEG-containing lipid is added to the composition, which allows for long circulation in blood and slower degradation of the formulation. The Liposomal suspension has been extruded and sized to 200nm in diameter and will not tend to precipitate upon storage. The concentration of clodronate in the suspension is ca. 5 mg/ml.
Upon request, the size can be reduced to 120-150nm with an extra extrusion step.
Control SUV PEG Liposomes
Control liposomes do not contain clodronate. Containing PBS only, they can be used for control experiments, in order to find out whether the effects observed after injection of clodronate liposomes are due to macrophage depletion exclusively. The Liposomal dispersion has been prepared with a special PEG-containing lipid which allows for long circulation in blood and slower degradation of the formulation. This formulation has been extruded and sized to 200nm in diameter which makes it the preferred control for the Clodronate SUV PEG liposomes.
Upon request, the size can be reduced to 120-150nm with an extra extrusion step.
| Weight | 0,2 kg |
|---|---|
| Quantity | 5 ml (5ml Clodronate SUV PEG Liposomes + 5ml Control SUV PEG Liposomes), 10 ml (10ml Clodronate SUV PEG Liposomes + 10ml Control SUV PEG Liposomes), 15 ml (15ml Clodronate SUV PEG Liposomes + 15ml Control SUV PEG Liposomes), 20 ml (20 ml Clodronate SUV PEG Liposomes + 20mlControl SUV PEG Liposomes), 25 ml (25ml Clodronate SUV PEG Liposomes + Control SUV PEG Liposomes), 30 ml (30ml Clodronate SUV PEG Liposomes + 30mlControl SUV PEG Liposomes), 40 ml (40ml Clodronate SUV PEG Liposomes + 40ml Control SUV PEG Liposomes), 50 ml (50ml Clodronate SUV PEG Liposomes + 50ml Control SUV PEG Liposomes), 60 ml (60ml Clodronate SUV PEG Liposomes + Control SUV PEG Liposomes), 70 ml (70ml Clodronate SUV PEG Liposomes + Control SUV PEG Liposomes), 80 ml (80ml Clodronate SUV PEG Liposomes + Control SUV PEG Liposomes), 90 ml (90ml Clodronate SUV PEG Liposomes + Control SUV PEG Liposomes), 100 ml (100ml Clodronate SUV PEG Liposomes + 100ml Control SUV PEG Liposomes), 150 ml (150ml Clodronate SUV PEG Liposomes + Control SUV PEG Liposomes), 200 ml (200ml Clodronate SUV PEG Liposomes + Control SUV PEG Liposomes), 250 ml (250ml Clodronate SUV PEG Liposomes + Control SUV PEG Liposomes), 300 ml (300ml Clodronate SUV PEG Liposomes + Control SUV PEG Liposomes), 350 ml (5ml Clodronate SUV PEG Liposomes + Control SUV PEG Liposomes), 400 ml (400ml Clodronate SUV PEG Liposomes + Control SUV PEG Liposomes), 450 ml (450ml Clodronate SUV PEG Liposomes + Control SUV PEG Liposomes), 500 ml (500ml Clodronate SUV PEG Liposomes + Control SUV PEG Liposomes) |
